Recurrent bladder carcinoma
Superficial bladder carcinoma is a frequently occurring disease. It is treated with surgery, named Transurethral Resection (TUR). After surgery these tumours often recur. Therefore after TUR, chemotherapeutics are often instilled in the bladder. We have tested IL-2 instillation in the bladder. Good therapeutic results were obtained.Presently we are trying to further improve this TUR-local-IL-2 therapy in patients with superficial bladder carcinoma.
Trial from 2011 to 2013
In 2011 - 2013 the Dept. Urology of VU University Medical Center, Amsterdam, the Netherlands organizes a multicenter phase II study for local IL-2 therapy, more info in Dutch.
The study will also be performed at the Academic Medical Center and the Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
For more information email to Dr J.J.L. Jacobs, blaaskanker@kankerimmuuntherapie.nl
The study will also be performed at the Academic Medical Center and the Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
For more information email to Dr J.J.L. Jacobs, blaaskanker@kankerimmuuntherapie.nl
References
Tubaro et al. (1995) Eur. Urol. 28, 297
W. Den Otter et al. (1998) J. Urol. 159, 1183
Grasso et al. (2001) J. Immunother. 24, 184
JJL Jacobs et al. The Open Cancer Immunology Journal 3 : 8-14 (2010).
D. Characiejus et al. Anticancer Research 31:699-703(2011).
W. Den Otter et al. (1998) J. Urol. 159, 1183
Grasso et al. (2001) J. Immunother. 24, 184
JJL Jacobs et al. The Open Cancer Immunology Journal 3 : 8-14 (2010).
D. Characiejus et al. Anticancer Research 31:699-703(2011).